تفاعل #440646
ord-c9a618e2e21b4dfc88878161f76a3197
معادلة التفاعل
المتفاعلات
الكواشف
لا شيء
ظروف التفاعل
الظروف التفصيلية
See reaction.notes.procedure_details.
الإجراء التجريبي
By a method analogous to that described in Example 3 starting from 4-(4-pyridyl)benzoic acid (199 mg, 1 mmol) and 1-(5-bromoindol-2-ylsulphonyl)piperazine (344 mg, 1 mmol, 1 mol eq.), was prepared 1-(5-bromoindol-2-ylsulphonyl)-4-[4-(4-pyridyl)benzoyl]piperazine methane sulphonic acid salt, (155 mg), 1H NMR (d6-DMSO) 2.3 (s, 3H), 3.0-3.3 (broad d, 4H), 3.4-3.8 (broad d, 4H), 7.0 (d, 1H), 7.45 (s, 2H), 7.6 (d, 2H), 7.95 (s, 1H), 8.0 (d, 2H), 8.25 (d, 2H), 8.9 (d, 2H), 12.4 (s, 1H), signals were also present due to ethanol (0.15 mol equiv.); MS (M+H)+ 525/527.