تفاعل #43811
ord-c0267d7a4d17472887b6e0ded77623d3
معادلة التفاعل
المتفاعلات
الكواشف
لا شيء
ظروف التفاعل
درجة الحرارة
70°CELSIUS
الظروف التفصيلية
See reaction.notes.procedure_details.
المعالجة
- 1استخلاصextracted with water
- 2استخلاصextracted with DCM
- 3غسيلThe organic layer was washed with water
- 4تركيزconcentrated
- 5أخرىpurified by preparative LCMS
الإجراء التجريبي
The product of step d.) was dissolved in 3 mL ethanol, treated with 1 M NaOH (500 μL), and heated to 70° C. for one hour. The reaction was diluted in DCM and extracted with water. The aqueous layer was acidified with 1 M HCl and extracted with DCM. The organic layer was washed with water, concentrated and purified by preparative LCMS to give the title compound. MS: ESI (positive): 334 (M+H).