تفاعل #436753

معادلة التفاعل

2-(2,3-dihydro-1H-imidazo[1,2-b]pyrazol-7-yl)ethylamine

ethyl formate

→

2-(2,3-dihydro-1H-imidazo[1,2-b]pyrazol-7-yl)ethylformamide

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةwas refluxed for 4.5 hours
2. 2
   أخرىAfter evaporation of the solvent in vacuo
3. 3
   أخرىthe residue was triturated with ethyl acetate
4. 4
   أخرىdried in vacuo

الإجراء التجريبي

A suspension of 2-(2,3-dihydro-1H-imidazo[1,2-b]pyrazol-7-yl)ethylamine (155 mg) in ethyl formate (3 ml) was refluxed for 4.5 hours. After evaporation of the solvent in vacuo, the residue was triturated with ethyl acetate and dried in vacuo to give 2-(2,3-dihydro-1H-imidazo[1,2-b]pyrazol-7-yl)ethylformamide (165 mg) as a solid.

المصدر