تفاعل #433603

ord-bf068f66c82e4be791691495db42806e

معادلة التفاعل

CN(C)CC=CC(=O)Nc1ccc2ncnc(Nc3cccc(I)c3)c2c1
Compound 5
CN(C)CC=CC(=O)Nc1ccc2ncnc(Nc3cccc(I)c3)c2c1
N-{4-[(3-iodophenyl)amino]quinazoline-6-yl}-4-(dimethylamino)-2-butenamide
CNc1ccccc1
methylaniline
→
CNCC=CC(=O)Nc1ccc2ncnc(Nc3cccc(I)c3)c2c1
N-{4-[(3-iodophenyl)amino]quinazoline-6-yl}-4-(methylamino)-2-butenamide

المتفاعلات

CN(C)CC=CC(=O)Nc1ccc2ncnc(Nc3cccc(I)c3)c2c1
Compound 5
CN(C)CC=CC(=O)Nc1ccc2ncnc(Nc3cccc(I)c3)c2c1
N-{4-[(3-iodophenyl)amino]quinazoline-6-yl}-4-(dimethylamino)-2-butenamide
CNc1ccccc1
methylaniline

الكواشف

لا شيء

ظروف التفاعل

الظروف التفصيلية
See reaction.notes.procedure_details.

الإجراء التجريبي

N-{4-[(3-iodophenyl)amino]quinazoline-6-yl}-4-(methylamino)-2-butenamide was prepared as described above in Compound 5, using methylaniline instead of dimethylamine in step (ii).

المصدر

DOI: 10.6084/m9.figshare.5104873.v1براءة الاختراع: US07172749B2uspto-grants-2007_02