تفاعل #4333

معادلة التفاعل

4,5-dichloro-2-nitroaniline

ethanolamine

→

2-amino-4-β-hydroxyethylamino-5-chloronitrobenzene

المذيبات

dioxane

dioxane

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةThe reaction mixture is heated for 6 hours
2. 2
   أخرىAfter dilution with water and neutralization with concentrated hydrochloric acid, the expected product precipitates

الإجراء التجريبي

0.11 mole (22.8 g) of 4,5-dichloro-2-nitroaniline is added to a solution of 0.55 mole (33.3 ml) of ethanolamine in 70 ml of dioxane. The reaction mixture is heated for 6 hours in refluxing dioxane. After dilution with water and neutralization with concentrated hydrochloric acid, the expected product precipitates.

المصدر