تفاعل #43313

معادلة التفاعل

Pyridinium p-toluenesulfonate

4-benzyloxy-1-{4-[(2-tetrahydropyranyl)oxy]phenyl}-1H-pyridin-2-one

→

title compound

المردود 98.0%

4-benzyloxy-1-(4-hydroxyphenyl)-1H-pyridin-2-one

المردود 98.0%

المذيبات

ethanol

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةrefluxed for an hour
2. 2
   أخرىThe reaction liquid
3. 3
   ترشيحthe precipitate was recovered by filtration
4. 4
   غسيلwashed with water and ethyl acetate

الإجراء التجريبي

Pyridinium p-toluenesulfonate (65 mg) was added to an ethanol solution (16 mL) of 4-benzyloxy-1-{4-[(2-tetrahydropyranyl)oxy]phenyl}-1H-pyridin-2-one (982 mg, 2.60 mmols) and refluxed for an hour. The reaction liquid was cooled to room temperature and the precipitate was recovered by filtration and washed with water and ethyl acetate to provide the title compound (746 mg, 98%).

المصدر