تفاعل #43258

معادلة التفاعل

2,4 dichloropyrimidine

4-fluoro-3-formylphenylboronic acid

→

5-(2-chloropyrimidin-4-yl) 2-fluorobenzaldehyde

المردود 40.0%

ظروف التفاعل

الإجراء التجريبي

2,4 dichloropyrimidine and 4-fluoro-3-formylphenylboronic acid was coupled following procedure A. The yield was 40%. LC-MS showed the product was >95% pure and had the expected M+H+ of 237.

المصدر