تفاعل #432223

معادلة التفاعل

2-Methyl-6-nitroquinoline

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title compound

6-Amino-2-methylquinoline

المذيبات

ethanol

ظروف التفاعل

المعالجة

1. 1
   أخرىThe catalyst was then removed by filtration
2. 2
   أخرىthe filtrate evaporated to small volume in vacuo
3. 3
   ترشيحthe resultant precipitate collected by filtration
4. 4
   غسيلwashed with ethanol and ether
5. 5
   أخرىdried

الإجراء التجريبي

2-Methyl-6-nitroquinoline (18.8 g) was stirred under a hydrogen atmosphere at 30 p.s.i. (equivalent to 206. 8 kPa) for 2 hours in ethanol solution containing 5% Pd/C. The catalyst was then removed by filtration, the filtrate evaporated to small volume in vacuo, and the resultant precipitate collected by filtration, washed with ethanol and ether, and dried to give the title compound, yield 13.2 g, m.p. 188°-189°.

المصدر