تفاعل #431514

معادلة التفاعل

6-((3R)-3-tert-Butoxycarbonylaminomethylpyrrolidin-1-yl)hexylamine

n-propyl isocyanate

4-amino-5-chloro-2-methoxybenzoic acid

→

4-amino-5-chloro-2-methoxy-N-((3R)-1-(6-(3-n-propylureido)hexyl)pyrrolidin-3-ylmethyl)benzamide

ظروف التفاعل

المعالجة

1. 1
   أخرىwas reacted

الإجراء التجريبي

6-((3R)-3-tert-Butoxycarbonylaminomethylpyrrolidin-1-yl)hexylamine (1.50 g) as starting compound was reacted and treated in the same manner as in Example 34 using n-propyl isocyanate (0.50 ml) and 4-amino-5-chloro-2-methoxybenzoic acid (1.01 g) to give 4-amino-5-chloro-2-methoxy-N-((3R)-1-(6-(3-n-propylureido)hexyl)pyrrolidin-3-ylmethyl)benzamide.

المصدر