تفاعل #430823

معادلة التفاعل

4-cyano-4'-hydroxybiphenyl

6-bromohexanol

potassium carbonate

→

4-cyano-4'-(6-hydroxyhexyloxy)biphenyl

المردود 48.0%

المذيبات

acetonitrile

ظروف التفاعل

المعالجة

1. 1
   أخرىThe obtained gray powder was recrystallized from methanol

الإجراء التجريبي

Using 5 g (25.6 mmol) of 4-cyano-4'-hydroxybiphenyl, 85 ml of acetonitrile, 4.63 g (25.6 mmol) of 6-bromohexanol and 7.09 g (51.2 mmol) of anhydrous potassium carbonate, synthetic treatment was carried out in the same manner as in Example 2. The obtained gray powder was recrystallized from methanol to obtain 3.6 g (yield: 48%) of 4-cyano-4'-(6-hydroxyhexyloxy)biphenyl (24) as a colorless powder.

المصدر