تفاعل #430034

معادلة التفاعل

Compound 36

tris(3-[([(3,5-diacetylphenyl)amino]carbonyl)amino]propyl)amine hexakis(amidinohydrazone)heptahydrochloride

3,5-Diacetylphenyl isocyanate

tris(3-aminopropyl)amine

→

tris(3-[([(3,5-diacetylphenyl)amino]carbonyl)amino]propyl)amine

المذيبات

tetrahydrofuran

ظروف التفاعل

المعالجة

1. 1
   ترشيحFiltration

الإجراء التجريبي

Compound 36, FIG. 7H.36: 3,5-Diacetylphenyl isocyanate (0.4 g) and tris(3-aminopropyl)amine (0.12 g) in tetrahydrofuran (5 mL) were stirred at r.t. for 30 min. Filtration gave 0.32 g of tris(3-[([(3,5-diacetylphenyl)amino]carbonyl)amino]propyl)amine, mp 147-8 C. This hexaketone (0.4 g) and aminoguanidine dihydrochloride (0.49 g) were heated in methanol (3 mL) for 4 hours. Addition of ethanol and filtration gave 0.58 g of tris(3-[([(3,5-diacetylphenyl)amino]carbonyl)amino]propyl)amine hexakis(amidinohydrazone)heptahydrochloride (Compound 36) as the dihydrate hemi-ethanolate, mp 250°-1° C. (dec).

المصدر