تفاعل #429239

معادلة التفاعل

p-toluene sulfonic acid

2-hydroxy-2-methylpropionic acid

m-xylene

→

tetramethyl glycolide

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةThe mixture was refluxed
2. 2
   أخرىto remove water

الإجراء التجريبي

Crude tetramethyl glycolide was prepared by direct liquid phase synthesis from 2-hydroxy-2-methylpropionic acid using m-xylene as the solvent and p-toluene sulfonic acid as the catalyst. The mixture was refluxed using a Dean-Stark tube to remove water.

المصدر