تفاعل #429216
ord-3f577259a7a748b98a15d36aa6b42723
معادلة التفاعل
methylene chloride
product
1-((6-chloro-1,3-benzodioxol-5-yl)methyl)-4-((4-methoxyphenyl)thio)-2-phenyl-1H-imidazole-5-carboxaldehyde
sodium cyanide
methanol
→
expected product
methyl 1-((6-chloro-1,3-benzodioxol-5-yl)methyl)-4-((4-methoxyphenyl)thio)-2-phenyl-1H-imidazole-5-carboxylate
المتفاعلات
الكواشف
المذيبات
ظروف التفاعل
الظروف التفصيلية
See reaction.notes.procedure_details.
الإجراء التجريبي
The operation is carried out as in Example 9 starting with 2 g of the product of Example 20 using 10 g of manganese oxide, 1 g of sodium cyanide, 200 ml of methanol, 40 ml of methylene chloride and 600 ul of acetic acid, in this way 1.64 g of expected product is obtained (M.p.=161° C.).