تفاعل #42774
ord-d432949c0c7046e1843b5cf1467f7cf1
معادلة التفاعل
الكواشف
لا شيء
المذيبات
ظروف التفاعل
الظروف التفصيلية
See reaction.notes.procedure_details.
المعالجة
- 1غسيلwashed with water (3×100 ml) and saturated brine (50 ml)
- 2تجفيفdried (MgSO4)
- 3ترشيحfiltered
- 4أخرىthe filtrate is evaporated
- 5أخرىto give a pale pink solid
الإجراء التجريبي
3-(4-Chlorophenyl)-7-hydroxy-2-isopropyl-chromen-4-one (2.3 g, 7.31 mmol) is suspended in dry dichloromethane (140 ml) at room temperature. N-iodosuccinimide (1.73 g, 7.67 mmol) is added, and the mixture is stirred vigorously at room temperature for 30 min. The mixture is diluted with dichloromethane (60 ml), washed with water (3×100 ml) and saturated brine (50 ml), dried (MgSO4) and filtered, and the filtrate is evaporated to give a pale pink solid.