تفاعل #426772

معادلة التفاعل

Hexane EtOAc

potassium t-butoxide

4-hydroxybenzaldehyde

diethyl 4-(6-methylbenzothiazol-2-yl)benzylphosphonate

→

title compound

المردود 67.0%

4-{(E)-2-[4-(6-Methyl-1,3-benzothiazol-2-yl)phenyl]ethenyl}phenol

المردود 67.0%

المذيبات

THF

THF

ظروف التفاعل

المعالجة

1. 1
   أخرىPrepared

الإجراء التجريبي

Prepared as described in the Alkene Formation section using diethyl 4-(6-methylbenzothiazol-2-yl)benzylphosphonate (0.10 g, 0.266 mmol) in dry THF (10 ml), potassium t-butoxide (0.063 g, 0.559 mmol) and 4-hydroxybenzaldehyde (0.033 g, 0.266 mmol) in dry THF (5 ml) to give the title compound (0.061 g, 67%) as a pale orange solid after work-up and flash chromatography (2:1 Hexane/EtOAc).

المصدر