تفاعل #426767

معادلة التفاعل

Hexane EtOAc

potassium t-butoxide

benzaldehyde

diethyl 4-(6-methylbenzothiazol-2-yl)benzylphosphonate

→

title compound

المردود 61.1%

6-Methyl-2-{4-[(E)-2-phenylethenyl]phenyl}-1,3-benzothiazole

المردود 61.1%

المذيبات

THF

THF

ظروف التفاعل

المعالجة

1. 1
   أخرىPrepared

الإجراء التجريبي

Prepared as described in the Alkene Formation section using diethyl 4-(6-methylbenzothiazol-2-yl)benzylphosphonate (0.30 g, 0.80 mmol) in dry THF (15 ml), potassium t-butoxide (0.10 g, 0.88 mmol) and benzaldehyde (0.085 g, 0.80 mmol) in dry THF (5 ml) to give the title compound (0.16 g, 60%) as a pale yellow solid after work-up and flash chromatography (2:1 Hexane/EtOAc).

المصدر