تفاعل #4265

معادلة التفاعل

11-chlorocarbonyl-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one

N-methyl-propargylamine

→

desired compound

5,11-Dihydro-11-[[N-methyl(2-propynyl)amino]carbonyl]-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one

ظروف التفاعل

الإجراء التجريبي

Analogously to Example C, using 27.3 g (0.1 mol) of 11-chlorocarbonyl-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one and 7.0 g (0.1 mol) of N-methyl-propargylamine, 27 g (88% of theory) of the desired compound are obtained.

المصدر