تفاعل #425212

معادلة التفاعل

(3aR,7aR)-3a-(1-methyl-1H-pyrazol-5-yl)hexahydro-1,3-benzodioxol-2-one

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title compound

المردود 22.0%

(1R,2R)-2-(1-Methyl-1H-pyrazol-5-yl)cyclohexanol

المردود 22.0%

المذيبات

THF

ظروف التفاعل

المعالجة

1. 1
   أخرىThe reaction and aftertreatment

الإجراء التجريبي

The reaction and aftertreatment were conducted in the same manner as in Example 167b by using the (3aR,7aR)-3a-(1-methyl-1H-pyrazol-5-yl)hexahydro-1,3-benzodioxol-2-one (760 mg, 3.42 mmol) prepared in Example 168b, palladium carbon (10%; 760 mg) and THF (10 mL), to yield the title compound (133 mg, 22%) as a colorless oil.

المصدر