تفاعل #424580
ord-c2e3305fb560461db910a7b100420e5b
معادلة التفاعل
water
methylenebis(phosphonic dichloride)
4-hydroxybenzophenone
pyridine
→
(4-benzoylbenzyl)phosphonic dichloride
الكواشف
لا شيء
المذيبات
ظروف التفاعل
الظروف التفصيلية
See reaction.notes.procedure_details.
المعالجة
- 1أخرىis formed
الإجراء التجريبي
A degradable linking agent is formed by reacting methylenebis(phosphonic dichloride) (1 eq) with 4-hydroxybenzophenone (2 eq) in anhydrous DCM using pyridine (2.5 eq) as a base. The resulting product can be converted into its salt to increase water solubility.