تفاعل #423800

ord-11b6609dde844f4bba738aaf36e88b03

معادلة التفاعل

OCC12CC3CC(CC(C3)C1)C2
1-adamantanemethanol
Cc1ccc(C#N)[nH]1
2-cyano-5-methylpyrrole
Cc1n[nH]c(C)c1B1OC(C)(C)C(C)(C)O1
3,5-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole
Cc1ccc(C#N)n1CC12CC3CC(CC(C)(C3)O1)C2
title compound
Cc1ccc(C#N)n1CC12CC3CC(CC(C)(C3)O1)C2
5-methyl-1-(3-methyl-2-oxa-tricyclo[3.3.1.13,7]dec-1-ylmethyl)-1H-pyrrole-2-carbonitrile

ظروف التفاعل

الظروف التفصيلية
See reaction.notes.procedure_details.

الإجراء التجريبي

The title compound was prepared by substituting 1-hydroxymethyl-3-methyl-2-oxadamantane for 1-adamantanemethanol and 2-cyano-5-methylpyrrole for 3,5-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole in EXAMPLE 2A.

المصدر

DOI: 10.6084/m9.figshare.5104873.v1براءة الاختراع: US08889675B2uspto-grants-2014_11