تفاعل #4215

معادلة التفاعل

N-[3-(Bromoacetyl)-2-oxo-1-imidazolidinyl]carbamic acid, 1,1-dimethylethyl ester

sodium iodide

→

title compound

N-[3-(iodoacetyl)-2-oxo-1-imidazolidinyl]carbamic acid, 1,1-dimethylethyl ester

المذيبات

acetone

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةat reflux for three hours
2. 2
   ترشيحfiltered hot through Celite
3. 3
   أخرىThe solution was evaporated in vacuo

الإجراء التجريبي

N-[3-(Bromoacetyl)-2-oxo-1-imidazolidinyl]carbamic acid, 1,1-dimethylethyl ester (20.9 g, 65 mmol) was dissolved in acetone (250 ml) containing sodium iodide (10.5 g, 70 mmol). The solution was stirred at reflux for three hours and filtered hot through Celite. The solution was evaporated in vacuo to give the title compound as a light yellow solid, 23.9 g.

المصدر