تفاعل #420683

معادلة التفاعل

7-(tert-Butyl-dimethyl-silanyloxy)-hept-2-yn-1-ol

Acetic acid 7-(tert-butyl-dimethyl-silanyloxy)-hept-2-ynyl ester

7-(tert-Butyl-dimethyl-silanyloxy)-hept-2-yn-1-ol

acetic anhydride

→

tert-Butyl-hex-5-ynyloxy-dimethyl-silane

المذيبات

pyridine

ظروف التفاعل

المعالجة

1. 1
   أخرىthe solvent was evaporated

الإجراء التجريبي

7-(tert-Butyl-dimethyl-silanyloxy)-hept-2-yn-1-ol (27); and Acetic acid 7-(tert-butyl-dimethyl-silanyloxy)-hept-2-ynyl ester (28, FIG. 4). A solution of 7-(tert-Butyl-dimethyl-silanyloxy)-hept-2-yn-1-ol (27) (4.507 g, 21 mmol) in pyridine (20 mL) was treated with acetic anhydride (3.0 mL, 31.8 mmol). After 18 hours, the solvent was evaporated and the residue co-evaporated with toluene. The residue was used directly in the next step.

المصدر