تفاعل #420610

معادلة التفاعل

tert-butyl 4-ethyl-4-ethoxycarbonylpiperidine-1-carboxylate

dichloromethane trifluoroacetic acid

→

4-ethoxycarbonyl-4-ethylpiperidine trifluoroacetate

المردود 73.0%

المذيبات

ظروف التفاعل

المعالجة

1. 1
   أخرىthe solvents are then evaporated off

الإجراء التجريبي

183 mg (0.64 mmol) of tert-butyl 4-ethyl-4-ethoxycarbonylpiperidine-1-carboxylate are diluted in 4 mL of an 8/2 dichloromethane/trifluoroacetic acid mixture. The solution is stirred at room temperature for 1 hour and the solvents are then evaporated off. 140 mg of 4-ethoxycarbonyl-4-ethylpiperidine trifluoroacetate in the form of an oil are obtained in a yield of 73%.

المصدر