تفاعل #41956

معادلة التفاعل

Chloroacetaldehyde diethyl acetal

potassium benzoate

potassium bromide

DMF

→

compound

المردود 34.1%

2-benzoyloxyacetaldehyde Diethyl Acetal

المردود 34.1%

المذيبات

ethyl acetate

water

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةby refluxing
2. 2
   ترشيحAfter filtration
3. 3
   غسيلthe organic layer was washed with water (30 mL)
4. 4
   تجفيفwas dried over anhydrous sodium sulfate
5. 5
   ترشيحSubsequent filtration and vacuum concentration

الإجراء التجريبي

Chloroacetaldehyde diethyl acetal (2.00 g), potassium benzoate (1.91 g), potassium bromide (0.30 g) and DMF (20 mL) were placed in a three-neck flask, followed by refluxing. Twenty hours later, the reaction mixture was cooled to room temperature, and water (30 mL) and ethyl acetate (80 mL) were added thereto, followed by stirring. After filtration, the organic layer was washed with water (30 mL) and was dried over anhydrous sodium sulfate. Subsequent filtration and vacuum concentration yielded the target compound (0.97 g) in a yield of 31%.

المصدر