تفاعل #419337

معادلة التفاعل

2-amino-4-chlorobenzenethiol

N,N-dimethylacrylamide

HOAc

→

solid

المردود 83.0%

3-((2-amino-4-chlorophenyl)thio)-N,N-dimethylpropanamide

المردود 83.0%

المذيبات

CH2Cl2

ظروف التفاعل

المعالجة

1. 1
   أخرىThe solvent was removed
2. 2
   أخرىpurified

الإجراء التجريبي

The solution of 2-amino-4-chlorobenzenethiol (824 mg, 5.126 mmol), N,N-dimethylacrylamide (512 mg, 5.162 mmol), and HOAc (1 ml) in CH2Cl2 (10 ml) was stirred at room temperature for 4 days. The solvent was removed and the residue was loaded on silica column and purified to yield a white solid (1.08 g, 83%).

المصدر