تفاعل #417926
ord-00145c8c545a46f1a638a2987364c249
معادلة التفاعل
sodium hydroxide
33
methyl 4-(undec-4Z-enyloxy)benzoate
→
white solid
المردود 98.1%
4-(undec-4Z-enyloxy)benzoic acid
المردود 98.1%
الكواشف
لا شيء
المذيبات
ظروف التفاعل
الظروف التفصيلية
See reaction.notes.procedure_details.
المعالجة
- 1درجة الحرارةThe solution is refluxed for 20 hours
- 2أخرىAfter evaporating off the solvent
- 3استخلاصextracted with DCM
الإجراء التجريبي
550 μL of 1 N sodium hydroxide solution (550 μmol) are added portionwise to 109 mg of 33 (358 μmol) in methanol (4 mL). The solution is refluxed for 20 hours. After evaporating off the solvent, the reaction medium is acidified with 0.5 N HCl and extracted with DCM. 102 mg of a white solid are obtained, i.e. a yield of 98%.