تفاعل #417901

معادلة التفاعل

phosphoryl chloride

dibenzo[f,h]quinoxaline-1-oxide

potassium carbonate

→

2-Chloro-Dibenzo[f,h]Quinoxaline

المردود 93.0%

المذيبات

water

ظروف التفاعل

المعالجة

1. 1
   أخرىobtained in the above Step 1
2. 2
   درجة الحرارةwhile being heated
3. 3
   درجة الحرارةunder reflux for 1 hour
4. 4
   ترشيحThis solution was filtered
5. 5
   غسيلthe obtained residue was washed with water
6. 6
   أخرىmethanol to give
7. 7
   أخرىthe object of the synthesis (as a pale yellow powder in a yield of 93%)
8. 8
   أخرىThe synthesis scheme of Step 2

الإجراء التجريبي

Next, 18 mL of phosphoryl chloride was dripped into 2.91 g of dibenzo[f,h]quinoxaline-1-oxide obtained in the above Step 1. This mixed solution was stirred while being heated under reflux for 1 hour. This mixed solution was poured into iced water, followed by addition of potassium carbonate so that the mixture was alkaline. This solution was filtered, and the obtained residue was washed with water and then methanol to give the object of the synthesis (as a pale yellow powder in a yield of 93%). The synthesis scheme of Step 2 is illustrated in the following (a″′-2-2).

المصدر