تفاعل #41784

معادلة التفاعل

2-Chloro-5-nitropyridine

dimethylamine

H2O

→

2-(dimethylamino)-5-nitropyridine

المذيبات

NMP

ظروف التفاعل

المعالجة

1. 1
   أخرىThe filtrate that formed
2. 2
   ترشيحwas filtered
3. 3
   أخرىdried

الإجراء التجريبي

2-Chloro-5-nitropyridine (1.0 eq) and dimethylamine (2 M in EtOH, 4.6 eq) in NMP were heated for 2 h at 100° C. The solution was then poured slowly into H2O. The filtrate that formed was filtered and dried to give 2-(dimethylamino)-5-nitropyridine.

المصدر