تفاعل #41648

معادلة التفاعل

4-(4-ethanesulfonyl-phenoxy)-5-fluoro-2-nitro-phenylamine

5-fluoro-4-(4-ethanesulfonyl-phenoxy)-2-nitro-phenylamine

1-(R)-pyrrolidin-2-yl-ethanol

→

(2R)-1-(1-(6-(4-ethanesulfonyl-phenoxy)-2-pyrrolidin-2-yl-3H-benzimidazol-5-yl)-pyrrolidin-2-yl)-ethanone

ظروف التفاعل

المعالجة

1. 1
   أخرىThe entitled compound was obtained as a pale yellow solid in the same method as in Example 369 or in accordance with the method

الإجراء التجريبي

The entitled compound was obtained as a pale yellow solid in the same method as in Example 369 or in accordance with the method or by combining it with an ordinary method but using 4-(4-ethanesulfonyl-phenoxy)-5-fluoro-2-nitro-phenylamine obtained in Example 259 (step 1) and 1-(R)-pyrrolidin-2-yl-ethanol.

المصدر