تفاعل #41604

معادلة التفاعل

2-fluorophenol

potassium carbonate

dimethylformamide

N-(4-benzyloxy-5-fluoro-2-nitrophenyl)pyrazinecarboxamide

→

compound

N-(4-benzyloxy-5-(2-fluorophenoxy)-2-nitrophenyl)pyrazinecarboxamide

المذيبات

water

ظروف التفاعل

المعالجة

1. 1
   أخرىthe reaction liquid
2. 2
   ترشيحThe resulting deposit was taken out through filtration

الإجراء التجريبي

0.54 ml of 2-fluorophenol and 2.53 g of potassium carbonate were added to a dimethylformamide (16 ml) solution of 2.14 g of N-(4-benzyloxy-5-fluoro-2-nitrophenyl)pyrazinecarboxamide, and the reaction liquid was stirred at 90° C. for 5 hours, and then water was added to it. The resulting deposit was taken out through filtration to obtain the entitled compound as a yellow solid.

المصدر