تفاعل #412212

معادلة التفاعل

3-[2-(4-amino{t-butoxycarbonylimino}methylphenyl)-ethoxy]nitrobenzene

3-[2-(4-Amino{t-butoxycarbonylimino}methylphenyl)ethoxy]nitro-benzene

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sub-title compound

Amino-3-[2-(4-amino{t-butoxycarbonylimino}methylphenyl)ethoxy]-benzene

المذيبات

EtOH

ظروف التفاعل

المعالجة

1. 1
   ترشيحAfter filtration through Celite the solvent
2. 2
   أخرىwas evaporated
3. 3
   أخرىThe residue was purified by preparative HPLC (60% CH3CN/aq:0.1M NH4OAc)

الإجراء التجريبي

A suspension of 3-[2-(4-amino{t-butoxycarbonylimino}methylphenyl)-ethoxy]nitrobenzene (1.47 g; 3.81 mmol; from step (iii) above) and Pd (0.236 g; 5% on charcoal) in EtOH (75 mL) was stirred under H2(g) (1 atm.) for 25 minutes. After filtration through Celite the solvent was evaporated. The residue was purified by preparative HPLC (60% CH3CN/aq:0.1M NH4OAc) to afford the sub-title compound. Yield: 1.02 g (75%).

المصدر