تفاعل #409943

ord-01302e7551d649d1bade33fd98e9c270

معادلة التفاعل

C[C@H](NC(=O)Cc1cccc([N+](=O)[O-])c1)C(=O)O
N-(3-nitrophenylacetyl)-L-alanine
CC[C@H](N)C(=O)OC.Cl
methyl (S)-2-aminobutanoate hydrochloride
→
CC[C@H](NC(=O)[C@H](C)NC(=O)Cc1cccc([N+](=O)[O-])c1)C(=O)OC
title compound
CC[C@H](NC(=O)[C@H](C)NC(=O)Cc1cccc([N+](=O)[O-])c1)C(=O)OC
Methyl N-[N-(3-nitrophenylacetyl)-L-alaninyl]-(S)-2-aminobutanoate

المتفاعلات

C[C@H](NC(=O)Cc1cccc([N+](=O)[O-])c1)C(=O)O
N-(3-nitrophenylacetyl)-L-alanine
CC[C@H](N)C(=O)OC.Cl
methyl (S)-2-aminobutanoate hydrochloride
—
solid

الكواشف

لا شيء

ظروف التفاعل

الظروف التفصيلية
See reaction.notes.procedure_details.

الإجراء التجريبي

Following General Procedure C and using N-(3-nitrophenylacetyl)-L-alanine (from Example D11 above) and methyl (S)-2-aminobutanoate hydrochloride (prepared from (S)-(+)-2-aminobutyric acid (Aldrich) using General Procedure H), the title compound was prepared as a solid (mp=154-157° C.).

المصدر

DOI: 10.6084/m9.figshare.5104873.v1براءة الاختراع: US06211235B1uspto-grants-2001_04