تفاعل #40823
ord-25cfcf96b25d4fc6b54c9b584a00826c
معادلة التفاعل
ethyl 5-(4-trifluoromethylphenyl)-6-phenylpyridine-2-carboxylate
ethyl 6-phenyl-5-(4-trifluoromethylphenyl)-pyridine-2-carboxylate
Compound 25
ethyl 6-phenyl-5-(4-trifluoromethylphenyl)-pyridine-2-carboxylate
DIBAL-H
→
title compound
5-(4-Trifluoromethylphenyl)-6-phenylpyridine-2-carbaldehyde
المتفاعلات
الكواشف
لا شيء
المذيبات
ظروف التفاعل
الظروف التفصيلية
See reaction.notes.procedure_details.
المعالجة
- 1أخرىwere reacted
الإجراء التجريبي
Following General Procedure L, ethyl 5-(4-trifluoromethylphenyl)-6-phenylpyridine-2-carboxylate (Compound 25, 74 mg, 0.20 mmol) and DIBAL-H (0.3 ml, 0.30 mmol, 1.0 M in hexane) in CH2Cl2 (3 ml) were reacted to produce the title compound after purification by column chromatography (silica gel, 15% ethyl acetate in hexane).