تفاعل #4074

معادلة التفاعل

(S)-2-(6-methoxy-2-naphthyl)propionic acid

hydrogen chloride

→

isobutyl (S)-2-(6-methoxy-2-naphthyl)propionate

المذيبات

isobutyl alcohol

ظروف التفاعل

المعالجة

1. 1
   workup.DISTILLATIONthe excess alcohol is distilled off in vacuo
2. 2
   أخرىthe residue is purified by chromatography

الإجراء التجريبي

A solution of 300 mg of (S)-2-(6-methoxy-2-naphthyl)propionic acid in 5 ml of isobutyl alcohol is saturated with hydrogen chloride. After 24 hours, the excess alcohol is distilled off in vacuo and the residue is purified by chromatography using an alumina substrate to yield isobutyl (S)-2-(6-methoxy-2-naphthyl)propionate.

المصدر