تفاعل #4073

ord-969a0003bb064226bfa65a3513e9c62c

معادلة التفاعل

COc1ccc2cc([C@H](C)C(=O)O)ccc2c1
(S)-2-(6-methoxy-2-naphthyl)-propionic acid
[Na+].[OH-]
sodium hydroxide
COc1ccc2cc([C@H](C)C(=O)[O-])ccc2c1.[Na+]
sodium (S)-2-(6-methoxy-2-naphthyl)propionate

المذيبات

ظروف التفاعل

الظروف التفصيلية
See reaction.notes.procedure_details.

المعالجة

  1. 1
    أخرىThe solvent is evaporated in vacuo
  2. 2
    أخرىfollowed by precipitation with ether

الإجراء التجريبي

To a solution of 300 mg of (S)-2-(6-methoxy-2-naphthyl)-propionic acid in 5 ml of methanol is added a 1 molar equivalent of sodium hydroxide, in the form of a 0.1N solution. The solvent is evaporated in vacuo and the residue is taken up in 2 ml of methanol, followed by precipitation with ether, to yield crude sodium (S)-2-(6-methoxy-2-naphthyl)propionate.

المصدر

DOI: 10.6084/m9.figshare.5104873.v1براءة الاختراع: US04723033uspto-grants-1988_02