تفاعل #4071

معادلة التفاعل

methyl α-(2-methylphenyl)-β-methoxyacrylate

N-bromosuccinimide

succinimide

→

colorless crystals

المردود 97.3%

Methyl α-(2-bromomethylphenyl)-β-methoxyacrylate

المردود 97.3%

المذيبات

CCl4

ظروف التفاعل

المعالجة

1. 1
   ترشيحThe mixture is filtered
2. 2
   أخرىthe filtrate is evaporated down
3. 3
   workup.DISSOLUTIONthe oil which remains is dissolved in about 5 ml of acetone
4. 4
   أخرىbrought to crystallization with n-hexane

الإجراء التجريبي

20.6 g of the methyl α-(2-methylphenyl)-β-methoxyacrylate obtained as described in method A, 17.65 g of N-bromosuccinimide, 0.2 g of azobisisobutyronitrile and 150 ml of CCl4 are slowly heated to 90° C. and kept at this temperature until all of the succinimide floats on the solvent. The mixture is filtered, the filtrate is evaporated down, and the oil which remains is dissolved in about 5 ml of acetone and brought to crystallization with n-hexane. 27.5 g of colorless crystals of melting point 86°-87° C. are obtained.

المصدر