تفاعل #40695

معادلة التفاعل

compound

benzyl 2-(3-methylphenoxy)-1-[(2-nitroanilino)methyl]ethylcarbamate

hydrobromide acetic acid

→

title compound

3-(3-methylphenoxy)-N1-(2-nitrophenyl)-1,2-propanediamine hydrobromide

المذيبات

dichloromethane

dichloromethane

ظروف التفاعل

المعالجة

1. 1
   غسيلwashed with saturated aqueous sodium hydrogen carbonate
2. 2
   تجفيفThe organic layer was dried over anhydrous sodium sulfate
3. 3
   أخرىthe solvent was evaporated

الإجراء التجريبي

To the compound obtained in Step 2 were added 30% hydrobromide/acetic acid (1 ml) and dichloromethane (2 ml), and the mixture was stirred at 0° C. for 2 hrs. The mixture was diluted with dichloromethane, and washed with saturated aqueous sodium hydrogen carbonate. The organic layer was dried over anhydrous sodium sulfate and the solvent was evaporated to give the title compound as a crude product.

المصدر