تفاعل #4069

معادلة التفاعل

N-bromosuccinimide

methyl phenylacetate

→

title compound

المردود 93.1%

Methyl Bromo-Phenylacetate

المردود 93.1%

المذيبات

carbon tetrachloride

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةto reflux
2. 2
   درجة الحرارةrefluxed for about 12 hours
3. 3
   ترشيحfiltered
4. 4
   تركيزThe filtrate was concentrated by evaporation under vacuum

الإجراء التجريبي

In this example, a mixture containing 5.93 g of N-bromosuccinimide, 5.0 g of methyl phenylacetate; and a catalytic amount (about 0.1 g) of benzoyl peroxide in 50 ml of carbon tetrachloride was warmed to reflux and then refluxed for about 12 hours. The mixture was then cooled to about 0° C. and filtered. The filtrate was concentrated by evaporation under vacuum affording 7.1 g of the title compound as an oil.

المصدر