تفاعل #4045

ord-a2d4c15aa91b4bc49e43d3bde49780ee

معادلة التفاعل

O=C(F)C(F)(OC(F)(F)C(F)(F)C(F)(F)F)C(F)(F)F
perfluoro-2-methyl-3-oxahexanoyl fluoride
C[Si](C)(C)[O-].[Na+]
sodium trimethylsilanolate
O=C([O-])C(F)(OC(F)(F)C(F)(F)C(F)(F)F)C(F)(F)F.[Na+]
Sodium perfluoro-2-methyl-3-oxahexanoate
المردود 69.3%

الكواشف

لا شيء

المذيبات

ظروف التفاعل

الظروف التفصيلية
See reaction.notes.procedure_details.

المعالجة

  1. 1
    أخرىa 2 h reaction time

الإجراء التجريبي

The procedure of Example 1 was followed using perfluoro-2-methyl-3-oxahexanoyl fluoride (16.6 g, 50 mmol), sodium trimethylsilanolate (5.6 g, 50 mmol), and dry tetrahydrofuran (100 mL), and a 2 h reaction time. Sodium perfluoro-2-methyl-3-oxahexanoate (12.2 g, 69% yield) was isolated as a white solid: The 19F NMR data were the same as reported in Example 15.

المصدر

DOI: 10.6084/m9.figshare.5104873.v1براءة الاختراع: US04723016uspto-grants-1988_02