تفاعل #4031

معادلة التفاعل

Methyl perfluorobutyrate

sodium trimethylsilanolate

→

sodium perfluorobutyrate

المردود 84.0%

المذيبات

ether

ظروف التفاعل

المعالجة

1. 1
   ترشيحThe solid was filtered under nitrogen
2. 2
   غسيلwashed with dry ether
3. 3
   أخرىdried under a stream of nitrogen

الإجراء التجريبي

Methyl perfluorobutyrate (12.81 g, 56 mmol) was added dropwise to a stirred solution of sodium trimethylsilanolate (6.3 g, 56 mmol) in dry ether (300 mL) at room temperature under nitrogen. The reaction mixture was stirred overnight. The solid was filtered under nitrogen, washed with dry ether, and dried under a stream of nitrogen to afford sodium perfluorobutyrate (11.1 g, 84% yield) as a white solid: 19F NMR (D2O) δ -79.6 (t, J=8 Hz, CF3 --, 3F), -117.2 (q, J=8 Hz, CF3CF2CF2 --, 2F), -126.2 ppm (s, CF3CF2 --, 2F). Anal. Calcd. for C4F7NaO2 : C, 20.36; F, 56.35; Na, 9.74. Found: C, 20.84, 20.61, 20.58; F, 56.68, 53.24; Na, 9.89, 9.65.

المصدر