تفاعل #3988

معادلة التفاعل

1-Methyl-3-[1-(naphth-2-ylmethyl)piperid-4-yl]urea

benzoyl chloride

pyridine

→

title compound

1-Benzoyl-1-methyl-3-[1-(naphth-2-ylmethyl)piperid-4-yl]urea

المذيبات

toluene

ظروف التفاعل

الإجراء التجريبي

1-Methyl-3-[1-(naphth-2-ylmethyl)piperid-4-yl]urea (1.4 g.) (prepared by reacting 4-amino-1-(naphth-2-ylmethyl)piperidine with methyl isocyanate) in toluene (30 cm3) was acylated using benzoyl chloride (0.92 g) in presence of pyridine (0.6 g) to give the title compound: m.p. of HCl, hemihydrate salt =164°-166° C.

المصدر