تفاعل #3839

معادلة التفاعل

4-(3-oxo-3H-benzo[d]isothiazol-2-yl)benzene sulfonamide

methyl thiosalicylate

→

title compound

المردود 92.7%

2-[2-(4-Sulfamoylphenylcarbamoyl)phenyldisulfanyl]benzoic acid, methyl ester

المردود 92.7%

المذيبات

methanol

tetrahydrofuran

ظروف التفاعل

المعالجة

1. 1
   أخرىThis compound was prepared
2. 2
   أخرىThe product was triturated with ether
3. 3
   ترشيحfiltered
4. 4
   غسيلwashed with ether
5. 5
   أخرىdried in vacuo

الإجراء التجريبي

This compound was prepared according to the method of Example 132 using a suspension of 0.46 g (1.5 mmol) of 4-(3-oxo-3H-benzo[d]isothiazol-2-yl)benzene sulfonamide in a mixture of 15 mL of methanol and 15 mL of tetrahydrofuran, and 0.27 g (1.6 mmol) of methyl thiosalicylate. The product was triturated with ether, filtered, washed with ether and dried in vacuo to give 0.66 g of the title compound, mp 288°-290° C.

المصدر