تفاعل #3784

معادلة التفاعل

1,2-bis(2-methyl-5-trimethylsilyl-3-thienyl)hexafluorocyclopentene

hydrobromic acid

→

1,2-bis(2-methyl-3-thienyl)hexafluorocyclopentene

المردود 98.0%

المذيبات

chloroform

ظروف التفاعل

المعالجة

1. 1
   أخرىto react for 6 hours under refluxing conditions
2. 2
   أخرىAfter the completion of the reaction
3. 3
   غسيلthe chloroform layer was washed with an aqueous solution of sodium bicarbonate
4. 4
   أخرىthe chloroform was removed under reduced pressures
5. 5
   أخرىThe reaction product was purified by silicagel column chromatogram

الإجراء التجريبي

1,2-bis(2-methyl-5-trimethylsilyl-3-thienyl)hexafluorocyclopentene (2.16 g, 0.005 mol) was dissolved in chloroform (200 ml) and was allowed to react for 6 hours under refluxing conditions by adding concentrated hydrobromic acid (10 ml) to the solution. After the completion of the reaction, the chloroform layer was washed with an aqueous solution of sodium bicarbonate and the chloroform was removed under reduced pressures. The reaction product was purified by silicagel column chromatogram to give 1,2-bis(2-methyl-3-thienyl)hexafluorocyclopentene (1.8 g, 0.0049 mol).

المصدر