تفاعل #3736

ord-aba789f7e6174c6e9200510395e30ecf

معادلة التفاعل

O=c1c2[nH]c(Cl)nc2n(CC2CC2)c(=O)n1CC1CC1
1,3-di-cyclopropylmethyl-8-chloro xanthine
C1CCNC1
pyrrolidine
O=c1c2[nH]c(N3CCCC3)nc2n(CC2CC2)c(=O)n1CC1CC1
title product
O=c1c2[nH]c(N3CCCC3)nc2n(CC2CC2)c(=O)n1CC1CC1
1,3-Di-cyclopropylmethyl-8-pyrrolidinyl Xanthine

الكواشف

لا شيء

ظروف التفاعل

الظروف التفصيلية
See reaction.notes.procedure_details.

الإجراء التجريبي

The title compound was prepared from 1,3-di-cyclopropylmethyl-8-chloro xanthine (0.3 g, 0.0011 mol) and pyrrolidine (0.2 g, 0.0028 mol) using an analogous procedure to that described in Example 19. The title product was obtained as a crystalline solid, m.pt. >250° C.

المصدر

DOI: 10.6084/m9.figshare.5104873.v1براءة الاختراع: US05734051uspto-grants-1998_03