تفاعل #367197

معادلة التفاعل

2,4-diamino-5-(3-hydroxy-4,5-dimethoxybenzyl)pyrimidine

propargyl chloride

→

title compound

2,4-Diamino-5-[3,4-dimethoxy-5-(2-propynyloxy)benzyl]pyrimidine

ظروف التفاعل

المعالجة

1. 1
   أخرىRecrystallization from 95% ethanol

الإجراء التجريبي

The title compound was prepared from 2,4-diamino-5-(3-hydroxy-4,5-dimethoxybenzyl)pyrimidine and propargyl chloride by the procedure of Example 1A. Recrystallization from 95% ethanol gave off-white needles (73%); mp 160°-161°. Anal. Calcd for C16H18N4O3 : C, 61.13; H, 5.77; N, 17.82. Found: C, 60.96; H, 5.80; N, 17.75.

المصدر