تفاعل #364069

معادلة التفاعل

1-t-Butoxycarbonyl-4-(2-methoxyphenyl)-1,2,3,6-tetrahydropyridine

hydrogen

→

aforementioned compound

المردود 79.2%

1-t-Butoxycarbonyl-4-(2-methoxyphenyl)piperidine

المردود 79.2%

المذيبات

methanol

ظروف التفاعل

المعالجة

1. 1
   ترشيحThe reaction solution was filtered
2. 2
   غسيلthe thus obtained residue was thoroughly washed with methanol
3. 3
   غسيلThen the filtrate and washed solution
4. 4
   أخرىevaporated under a reduced pressure
5. 5
   أخرىto obtain

الإجراء التجريبي

1-t-Butoxycarbonyl-4-(2-methoxyphenyl)-1,2,3,6-tetrahydropyridine (150 mg, 0.52 mmol) and 10% palladium-carbon (30 mg) were stirred in methanol for two nights in an atmosphere of hydrogen. The reaction solution was filtered and the thus obtained residue was thoroughly washed with methanol. Then the filtrate and washed solution were combined and evaporated under a reduced pressure to obtain 120 mg of the aforementioned compound of interest (0.42 mmol, 81% in yield).

المصدر