تفاعل #360940

معادلة التفاعل

5-amino-2-mercaptobenzimidazole

dodecanoyl chloride

→

compound ( 8 )

المردود 103.6%

5-dodecanoylamino-2-mercaptobenzimidazole

المردود 103.6%

المذيبات

pyridine

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةunder cooling with ice
2. 2
   ترشيحThe formed crystals were filtered off
3. 3
   أخرىrecrystallized from water-
4. 4
   workup.ADDITIONcontaining methanol

الإجراء التجريبي

5 g of 5-amino-2-mercaptobenzimidazole was dissolved in 50 ml of pyridine and 7.95 g of dodecanoyl chloride was added dropwise thereto under cooling with ice. After stirring, for 3 hours at room temperature, the solution was poured into ice-water. The formed crystals were filtered off and recrystallized from water-containing methanol to obtain 10.9 g of compound (8).

المصدر