تفاعل #358289

معادلة التفاعل

4-(2-Methoxy-5-nitro-phenyl)-morpholine

→

4-methoxy-3-morpholin-4-yl-phenylamine

المردود 70.4%

المذيبات

ethanol

ظروف التفاعل

المعالجة

1. 1
   ترشيحthe catalyst was filtered off
2. 2
   أخرىthe solvent was evaporated

الإجراء التجريبي

4-(2-Methoxy-5-nitro-phenyl)-morpholine (w, 390 mg) was dissolved in 10 mL ethanol and reduced under 1 atm H2 using 10% Pd—C as a catalyst. After 14 hours, the catalyst was filtered off and the solvent was evaporated, affording 240 mg 4-methoxy-3-morpholin-4-yl-phenylamine (x) which was used without further purification: m/e: 208.12, MS (ES+): 209.2.

المصدر