تفاعل #357744

معادلة التفاعل

tert-butyl 4-[2-(trifluoromethyl)phenyl]-3,6-dihydropyridine-1(2H)-carboxylate

trifluoroacetic acid

→

4-[2-(Trifluoromethyl)phenyl]-1,2,3,6-tetrahydropyridine

المذيبات

methylene chloride

ظروف التفاعل

المعالجة

1. 1
   تركيزthe solution was concentrated
2. 2
   أخرىto give an oil

الإجراء التجريبي

To a solution of tert-butyl 4-[2-(trifluoromethyl)phenyl]-3,6-dihydropyridine-1(2H)-carboxylate (200 mg, 0.61 mmol) in methylene chloride (5 mL) was added trifluoroacetic acid (2.5 mL). After being stirred at room temperature for 45 min, the solution was concentrated to give an oil. MS calculated for C12H12F3N: (M+H) 228; found 228.1.

المصدر