تفاعل #357589

ord-dec0359e9ebe43b093abf9c39425d7e2

معادلة التفاعل

Fc1ccc(-c2csc3cc(OCCCBr)ccc23)cc1
6-(3-Bromo-propoxy)-3-(4-fluoro-phenyl)-benzo[b]thiophene
COCCNCCOC
bis(2-methoxyethyl)amine
COCCN(CCCOc1ccc2c(-c3ccc(F)cc3)csc2c1)CCOC
{3-[3-(4-Fluoro-phenyl)-benzo[b]thiophen-6-yloxy]-propyl}-bis-(2-methoxy-ethyl)-amine

ظروف التفاعل

الظروف التفصيلية
See reaction.notes.procedure_details.

الإجراء التجريبي

In analogy to example 3.1, 6-(3-Bromo-propoxy)-3-(4-fluoro-phenyl)-benzo[b]thiophene and bis(2-methoxyethyl)amine were converted to yield {3-[3-(4-Fluoro-phenyl)-benzo[b]thiophen-6-yloxy]-propyl}-bis-(2-methoxy-ethyl)-amine as colorless oil, MS: 418 (MH+).

المصدر

DOI: 10.6084/m9.figshare.5104873.v1براءة الاختراع: US07449483B2uspto-grants-2008_11